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ATRN-UQCRB Fusion FISH Probe

The ATRN-UQCRB Fusion FISH Probe is used to confirm a fusion of the ATRN and UQCRB genes. The fusion of the ATRN and UQCRB genes has been associated with Sarcoma, and Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ATRN-UQCRB-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ATRN-UQCRB-20-RERE 20 (40 μL) 200 μL
ATRN-UQCRB-20-REOR 20 (40 μL) 200 μL
ATRN-UQCRB-20-REGO 20 (40 μL) 200 μL
ATRN-UQCRB-20-REGR 20 (40 μL) 200 μL
ATRN-UQCRB-20-REAQ 20 (40 μL) 200 μL
ATRN-UQCRB-20-ORRE 20 (40 μL) 200 μL
ATRN-UQCRB-20-OROR 20 (40 μL) 200 μL
ATRN-UQCRB-20-ORGO 20 (40 μL) 200 μL
ATRN-UQCRB-20-ORAQ 20 (40 μL) 200 μL
ATRN-UQCRB-20-GORE 20 (40 μL) 200 μL
ATRN-UQCRB-20-GOOR 20 (40 μL) 200 μL
ATRN-UQCRB-20-GOGO 20 (40 μL) 200 μL
ATRN-UQCRB-20-GOGR 20 (40 μL) 200 μL
ATRN-UQCRB-20-GOAQ 20 (40 μL) 200 μL
ATRN-UQCRB-20-GRRE 20 (40 μL) 200 μL
ATRN-UQCRB-20-GROR 20 (40 μL) 200 μL
ATRN-UQCRB-20-GRGO 20 (40 μL) 200 μL
ATRN-UQCRB-20-GRGR 20 (40 μL) 200 μL
ATRN-UQCRB-20-GRAQ 20 (40 μL) 200 μL
ATRN-UQCRB-20-AQRE 20 (40 μL) 200 μL
ATRN-UQCRB-20-AQOR 20 (40 μL) 200 μL
ATRN-UQCRB-20-AQGO 20 (40 μL) 200 μL
ATRN-UQCRB-20-AQGR 20 (40 μL) 200 μL
ATRN-UQCRB-20-AQAQ 20 (40 μL) 200 μL

UQCRB Gene Summary

This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X. [provided by RefSeq, Dec 2011]

Gene Name: Ubiquinol-cytochrome C Reductase Binding Protein

Chromosome: CHR8: 97239303 -97247862

Locus: 8q22.1

ATRN Gene Summary

This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016]

Gene Name: Attractin

Chromosome: CHR20: 3451664 -3631769

Locus: 20p13

Gene Diseases

The ATRN UQCRB Fusion has been associated with the following diseases:

Disease Name
Sarcoma
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.