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B4GALT3-ERO1LB Fusion FISH Probe

The B4GALT3-ERO1LB Fusion FISH Probe is used to confirm a fusion of the B4GALT3 and ERO1LB genes. The fusion of the B4GALT3 and ERO1LB genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
B4GALT3-ERO1LB-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-RERE 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-REOR 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-REGO 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-REGR 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-REAQ 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-ORRE 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-OROR 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-ORGO 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-ORAQ 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GORE 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GOOR 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GOGO 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GOGR 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GOAQ 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GRRE 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GROR 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GRGO 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GRGR 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-GRAQ 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-AQRE 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-AQOR 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-AQGO 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-AQGR 20 (40 μL) 200 μL
B4GALT3-ERO1LB-20-AQAQ 20 (40 μL) 200 μL

B4GALT3 Gene Summary

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]

Gene Name: Beta-1,4-galactosyltransferase 3

Chromosome: CHR1: 161141099 -161147758

Locus: 1q23.3

Gene Diseases

The B4GALT3 ERO1LB Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.