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BACE2-SRGAP1 Fusion FISH Probe

The BACE2-SRGAP1 Fusion FISH Probe is used to confirm a fusion of the BACE2 and SRGAP1 genes. The fusion of the BACE2 and SRGAP1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BACE2-SRGAP1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
BACE2-SRGAP1-20-RERE 20 (40 μL) 200 μL
BACE2-SRGAP1-20-REOR 20 (40 μL) 200 μL
BACE2-SRGAP1-20-REGO 20 (40 μL) 200 μL
BACE2-SRGAP1-20-REGR 20 (40 μL) 200 μL
BACE2-SRGAP1-20-REAQ 20 (40 μL) 200 μL
BACE2-SRGAP1-20-ORRE 20 (40 μL) 200 μL
BACE2-SRGAP1-20-OROR 20 (40 μL) 200 μL
BACE2-SRGAP1-20-ORGO 20 (40 μL) 200 μL
BACE2-SRGAP1-20-ORAQ 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GORE 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GOOR 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GOGO 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GOGR 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GOAQ 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GRRE 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GROR 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GRGO 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GRGR 20 (40 μL) 200 μL
BACE2-SRGAP1-20-GRAQ 20 (40 μL) 200 μL
BACE2-SRGAP1-20-AQRE 20 (40 μL) 200 μL
BACE2-SRGAP1-20-AQOR 20 (40 μL) 200 μL
BACE2-SRGAP1-20-AQGO 20 (40 μL) 200 μL
BACE2-SRGAP1-20-AQGR 20 (40 μL) 200 μL
BACE2-SRGAP1-20-AQAQ 20 (40 μL) 200 μL

BACE2 Gene Summary

This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Gene Name: Beta-site APP-cleaving Enzyme 2

Chromosome: CHR21: 42539727 -42648524

Locus: 21q22.2-q22.3

SRGAP1 Gene Summary

The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016]

Gene Name: SLIT-ROBO Rho GTPase Activating Protein 1

Chromosome: CHR12: 64238540 -64541613

Locus: 12q14.2

Gene Diseases

The BACE2 SRGAP1 Fusion has been associated with the following diseases:

Disease Name
Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.