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BAZ2B-ITGB6 Fusion FISH Probe

The BAZ2B-ITGB6 Fusion FISH Probe is used to confirm a fusion of the BAZ2B and ITGB6 genes. The fusion of the BAZ2B and ITGB6 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BAZ2B-ITGB6-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-RERE 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-REOR 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-REGO 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-REGR 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-REAQ 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-ORRE 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-OROR 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-ORGO 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-ORAQ 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GORE 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GOOR 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GOGO 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GOGR 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GOAQ 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GRRE 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GROR 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GRGO 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GRGR 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-GRAQ 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-AQRE 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-AQOR 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-AQGO 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-AQGR 20 (40 μL) 200 μL
BAZ2B-ITGB6-20-AQAQ 20 (40 μL) 200 μL

ITGB6 Gene Summary

This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Gene Name: Integrin Subunit Beta 6

Chromosome: CHR2: 160958232 -161056590

Locus: 2q24.2

BAZ2B Gene Summary

This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

Gene Name: Bromodomain Adjacent To Zinc Finger Domain 2B

Chromosome: CHR2: 160175489 -160473059

Locus: 2q24.2

Gene Diseases

The BAZ2B ITGB6 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.