BBS2-ADAT1 Fusion FISH Probe
The BBS2-ADAT1 Fusion FISH Probe is used to confirm a fusion of the BBS2 and ADAT1 genes. The fusion of the BBS2 and ADAT1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BBS2-ADAT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-RERE | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-REOR | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-REGO | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-REGR | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-REAQ | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-ORRE | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-OROR | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-ORGO | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GORE | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GOOR | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GOGO | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GOGR | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GRRE | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GROR | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GRGO | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GRGR | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-AQRE | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-AQOR | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-AQGO | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-AQGR | 20 (40 μL) | 200 μL |
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| BBS2-ADAT1-20-AQAQ | 20 (40 μL) | 200 μL |
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BBS2 Gene Summary
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins.[provided by RefSeq, Oct 2014]
Gene Name: Bardet-Biedl Syndrome 2
Chromosome: CHR16: 56518258 -56554008
Locus: 16q13
ADAT1 Gene Summary
This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Gene Name: Adenosine Deaminase, TRNA Specific 1
Chromosome: CHR16: 75632246 -75657221
Locus: 16q23.1
Gene Diseases
The BBS2 ADAT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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