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BBX-DGKG Fusion FISH Probe

The BBX-DGKG Fusion FISH Probe is used to confirm a fusion of the BBX and DGKG genes. The fusion of the BBX and DGKG genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BBX-DGKG-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
BBX-DGKG-20-RERE 20 (40 μL) 200 μL
BBX-DGKG-20-REOR 20 (40 μL) 200 μL
BBX-DGKG-20-REGO 20 (40 μL) 200 μL
BBX-DGKG-20-REGR 20 (40 μL) 200 μL
BBX-DGKG-20-REAQ 20 (40 μL) 200 μL
BBX-DGKG-20-ORRE 20 (40 μL) 200 μL
BBX-DGKG-20-OROR 20 (40 μL) 200 μL
BBX-DGKG-20-ORGO 20 (40 μL) 200 μL
BBX-DGKG-20-ORAQ 20 (40 μL) 200 μL
BBX-DGKG-20-GORE 20 (40 μL) 200 μL
BBX-DGKG-20-GOOR 20 (40 μL) 200 μL
BBX-DGKG-20-GOGO 20 (40 μL) 200 μL
BBX-DGKG-20-GOGR 20 (40 μL) 200 μL
BBX-DGKG-20-GOAQ 20 (40 μL) 200 μL
BBX-DGKG-20-GRRE 20 (40 μL) 200 μL
BBX-DGKG-20-GROR 20 (40 μL) 200 μL
BBX-DGKG-20-GRGO 20 (40 μL) 200 μL
BBX-DGKG-20-GRGR 20 (40 μL) 200 μL
BBX-DGKG-20-GRAQ 20 (40 μL) 200 μL
BBX-DGKG-20-AQRE 20 (40 μL) 200 μL
BBX-DGKG-20-AQOR 20 (40 μL) 200 μL
BBX-DGKG-20-AQGO 20 (40 μL) 200 μL
BBX-DGKG-20-AQGR 20 (40 μL) 200 μL
BBX-DGKG-20-AQAQ 20 (40 μL) 200 μL

DGKG Gene Summary

This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Diacylglycerol Kinase Gamma

Chromosome: CHR3: 185864989 -186080023

Locus: 3q27.2-q27.3

BBX Gene Summary

The BBX, HMG-box Containing (BBX) gene is located on chr3 :107241782-107530049 at 3q13.12.

Gene Name: BBX, HMG-box Containing

Chromosome: CHR3: 107241782 -107530049

Locus: 3q13.12

Gene Diseases

The BBX DGKG Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.