BBX-RB1 Fusion FISH Probe
The BBX-RB1 Fusion FISH Probe is used to confirm a fusion of the BBX and RB1 genes. The fusion of the BBX and RB1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BBX-RB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-RERE | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-REOR | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-REGO | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-REGR | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-REAQ | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-ORRE | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-OROR | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-ORGO | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GORE | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GOOR | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GOGO | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GOGR | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GRRE | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GROR | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GRGO | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GRGR | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-AQRE | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-AQOR | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-AQGO | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-AQGR | 20 (40 μL) | 200 μL |
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| BBX-RB1-20-AQAQ | 20 (40 μL) | 200 μL |
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RB1 Gene Summary
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Gene Name: RB Transcriptional Corepressor 1
Chromosome: CHR13: 48877882 -49056026
Locus: 13q14.2
BBX Gene Summary
The BBX, HMG-box Containing (BBX) gene is located on chr3 :107241782-107530049 at 3q13.12.
Gene Name: BBX, HMG-box Containing
Chromosome: CHR3: 107241782 -107530049
Locus: 3q13.12
Gene Diseases
The BBX RB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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