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BCAP31-HMGB3 Fusion FISH Probe

The BCAP31-HMGB3 Fusion FISH Probe is used to confirm a fusion of the BCAP31 and HMGB3 genes. The fusion of the BCAP31 and HMGB3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BCAP31-HMGB3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
BCAP31-HMGB3-20-RERE 20 (40 μL) 200 μL
BCAP31-HMGB3-20-REOR 20 (40 μL) 200 μL
BCAP31-HMGB3-20-REGO 20 (40 μL) 200 μL
BCAP31-HMGB3-20-REGR 20 (40 μL) 200 μL
BCAP31-HMGB3-20-REAQ 20 (40 μL) 200 μL
BCAP31-HMGB3-20-ORRE 20 (40 μL) 200 μL
BCAP31-HMGB3-20-OROR 20 (40 μL) 200 μL
BCAP31-HMGB3-20-ORGO 20 (40 μL) 200 μL
BCAP31-HMGB3-20-ORAQ 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GORE 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GOOR 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GOGO 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GOGR 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GOAQ 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GRRE 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GROR 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GRGO 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GRGR 20 (40 μL) 200 μL
BCAP31-HMGB3-20-GRAQ 20 (40 μL) 200 μL
BCAP31-HMGB3-20-AQRE 20 (40 μL) 200 μL
BCAP31-HMGB3-20-AQOR 20 (40 μL) 200 μL
BCAP31-HMGB3-20-AQGO 20 (40 μL) 200 μL
BCAP31-HMGB3-20-AQGR 20 (40 μL) 200 μL
BCAP31-HMGB3-20-AQAQ 20 (40 μL) 200 μL

HMGB3 Gene Summary

This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Gene Name: High Mobility Group Box 3

Chromosome: CHRX: 150151762 -150159248

Locus: Xq28

BCAP31 Gene Summary

This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012]

Gene Name: B-cell Receptor Associated Protein 31

Chromosome: CHRX: 152965946 -152990201

Locus: Xq28

Gene Diseases

The BCAP31 HMGB3 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.