BCAR3-ODF3L2 Fusion FISH Probe
The BCAR3-ODF3L2 Fusion FISH Probe is used to confirm a fusion of the BCAR3 and ODF3L2 genes. The fusion of the BCAR3 and ODF3L2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCAR3-ODF3L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-RERE | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-REOR | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-REGO | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-REGR | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-REAQ | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-ORRE | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-OROR | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-ORGO | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GORE | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GOOR | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GOGO | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GOGR | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GRRE | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GROR | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GRGO | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GRGR | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-AQRE | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-AQOR | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-AQGO | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-AQGR | 20 (40 μL) | 200 μL |
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| BCAR3-ODF3L2-20-AQAQ | 20 (40 μL) | 200 μL |
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BCAR3 Gene Summary
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Name: BCAR3, NSP Family Adaptor Protein
Chromosome: CHR1: 94027348 -94147385
Locus: 1p22.1
ODF3L2 Gene Summary
The Outer Dense Fiber Of Sperm Tails 3 Like 2 (ODF3L2) gene is located on chr19 :463345-474983 at 19p13.3.
Gene Name: Outer Dense Fiber Of Sperm Tails 3 Like 2
Chromosome: CHR19: 463345 -474983
Locus: 19p13.3
Gene Diseases
The BCAR3 ODF3L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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