BCCIP-C10ORF137 Fusion FISH Probe
The BCCIP-C10ORF137 Fusion FISH Probe is used to confirm a fusion of the BCCIP and C10ORF137 genes. The fusion of the BCCIP and C10ORF137 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCCIP-C10ORF137-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-RERE | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-REOR | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-REGO | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-REGR | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-REAQ | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-ORRE | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-OROR | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-ORGO | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GORE | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GOOR | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GOGO | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GOGR | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GRRE | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GROR | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GRGO | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GRGR | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-AQRE | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-AQOR | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-AQGO | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-AQGR | 20 (40 μL) | 200 μL |
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| BCCIP-C10ORF137-20-AQAQ | 20 (40 μL) | 200 μL |
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BCCIP Gene Summary
This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: BRCA2 And CDKN1A Interacting Protein
Chromosome: CHR10: 127512103 -127542264
Locus: 10q26.2
Gene Diseases
The BCCIP C10ORF137 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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