BCKDHA-TMEM91 Fusion FISH Probe
The BCKDHA-TMEM91 Fusion FISH Probe is used to confirm a fusion of the BCKDHA and TMEM91 genes. The fusion of the BCKDHA and TMEM91 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCKDHA-TMEM91-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-RERE | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-REOR | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-REGO | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-REGR | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-REAQ | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-ORRE | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-OROR | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-ORGO | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GORE | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GOOR | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GOGO | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GOGR | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GRRE | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GROR | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GRGO | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GRGR | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-AQRE | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-AQOR | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-AQGO | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-AQGR | 20 (40 μL) | 200 μL |
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| BCKDHA-TMEM91-20-AQAQ | 20 (40 μL) | 200 μL |
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BCKDHA Gene Summary
The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Name: Branched Chain Keto Acid Dehydrogenase E1, Alpha Polypeptide
Chromosome: CHR19: 41903693 -41930910
Locus: 19q13.2
TMEM91 Gene Summary
The Transmembrane Protein 91 (TMEM91) gene is located on chr19 :41869870-41889987 at 19q13.2.
Gene Name: Transmembrane Protein 91
Chromosome: CHR19: 41869870 -41889987
Locus: 19q13.2
Gene Diseases
The BCKDHA TMEM91 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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