BCL7B-TBL2 Fusion FISH Probe
The BCL7B-TBL2 Fusion FISH Probe is used to confirm a fusion of the BCL7B and TBL2 genes. The fusion of the BCL7B and TBL2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCL7B-TBL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-RERE | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-REOR | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-REGO | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-REGR | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-REAQ | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-ORRE | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-OROR | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-ORGO | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GORE | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GOOR | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GOGO | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GOGR | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GRRE | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GROR | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GRGO | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GRGR | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-AQRE | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-AQOR | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-AQGO | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-AQGR | 20 (40 μL) | 200 μL |
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| BCL7B-TBL2-20-AQAQ | 20 (40 μL) | 200 μL |
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BCL7B Gene Summary
This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: BCL Tumor Suppressor 7B
Chromosome: CHR7: 72950682 -72972065
Locus: 7q11.23
TBL2 Gene Summary
This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq, Jul 2008]
Gene Name: Transducin Beta Like 2
Chromosome: CHR7: 72983276 -72993013
Locus: 7q11.23
Gene Diseases
The BCL7B TBL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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