BCLAF1-MAP7 Fusion FISH Probe
The BCLAF1-MAP7 Fusion FISH Probe is used to confirm a fusion of the BCLAF1 and MAP7 genes. The fusion of the BCLAF1 and MAP7 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCLAF1-MAP7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-RERE | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-REOR | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-REGO | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-REGR | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-REAQ | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-ORRE | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-OROR | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-ORGO | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GORE | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GOOR | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GOGO | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GOGR | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GRRE | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GROR | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GRGO | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GRGR | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-AQRE | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-AQOR | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-AQGO | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-AQGR | 20 (40 μL) | 200 μL |
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| BCLAF1-MAP7-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP7 Gene Summary
The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Microtubule Associated Protein 7
Chromosome: CHR6: 136663418 -136871957
Locus: 6q23.3
BCLAF1 Gene Summary
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: BCL2 Associated Transcription Factor 1
Chromosome: CHR6: 136578000 -136610989
Locus: 6q23.3
Gene Diseases
The BCLAF1 MAP7 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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