BCOR-L3MBTL2 Fusion FISH Probe
The BCOR-L3MBTL2 Fusion FISH Probe is used to confirm a fusion of the BCOR and L3MBTL2 genes. The fusion of the BCOR and L3MBTL2 genes has been associated with Brain Lower Grade Glioma, and Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCOR-L3MBTL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-RERE | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-REOR | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-REGO | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-REGR | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-REAQ | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-ORRE | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-OROR | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-ORGO | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GORE | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GOOR | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GOGO | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GOGR | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GRRE | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GROR | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GRGO | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GRGR | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-AQRE | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-AQOR | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-AQGO | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-AQGR | 20 (40 μL) | 200 μL |
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| BCOR-L3MBTL2-20-AQAQ | 20 (40 μL) | 200 μL |
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BCOR Gene Summary
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]
Gene Name: BCL6 Corepressor
Chromosome: CHRX: 39910498 -40036582
Locus: Xp11.4
L3MBTL2 Gene Summary
The L3MBTL2, Polycomb Repressive Complex 1 Subunit (L3MBTL2) gene is located on chr22 :41601312-41627275 at 22q13.2.
Gene Name: L3MBTL2, Polycomb Repressive Complex 1 Subunit
Chromosome: CHR22: 41601312 -41627275
Locus: 22q13.2
Gene Diseases
The BCOR L3MBTL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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