BCOR-PHEX Fusion FISH Probe
The BCOR-PHEX Fusion FISH Probe is used to confirm a fusion of the BCOR and PHEX genes. The fusion of the BCOR and PHEX genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCOR-PHEX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-RERE | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-REOR | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-REGO | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-REGR | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-REAQ | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-ORRE | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-OROR | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-ORGO | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-ORAQ | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GORE | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GOOR | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GOGO | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GOGR | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GOAQ | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GRRE | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GROR | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GRGO | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GRGR | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-GRAQ | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-AQRE | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-AQOR | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-AQGO | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-AQGR | 20 (40 μL) | 200 μL |
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| BCOR-PHEX-20-AQAQ | 20 (40 μL) | 200 μL |
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PHEX Gene Summary
The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Phosphate Regulating Endopeptidase Homolog X-linked
Chromosome: CHRX: 22050920 -22266478
Locus: Xp22.11
BCOR Gene Summary
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]
Gene Name: BCL6 Corepressor
Chromosome: CHRX: 39910498 -40036582
Locus: Xp11.4
Gene Diseases
The BCOR PHEX Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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