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BICD1-SOX5 Fusion FISH Probe

The BICD1-SOX5 Fusion FISH Probe is used to confirm a fusion of the BICD1 and SOX5 genes. The fusion of the BICD1 and SOX5 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BICD1-SOX5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
BICD1-SOX5-20-RERE 20 (40 μL) 200 μL
BICD1-SOX5-20-REOR 20 (40 μL) 200 μL
BICD1-SOX5-20-REGO 20 (40 μL) 200 μL
BICD1-SOX5-20-REGR 20 (40 μL) 200 μL
BICD1-SOX5-20-REAQ 20 (40 μL) 200 μL
BICD1-SOX5-20-ORRE 20 (40 μL) 200 μL
BICD1-SOX5-20-OROR 20 (40 μL) 200 μL
BICD1-SOX5-20-ORGO 20 (40 μL) 200 μL
BICD1-SOX5-20-ORAQ 20 (40 μL) 200 μL
BICD1-SOX5-20-GORE 20 (40 μL) 200 μL
BICD1-SOX5-20-GOOR 20 (40 μL) 200 μL
BICD1-SOX5-20-GOGO 20 (40 μL) 200 μL
BICD1-SOX5-20-GOGR 20 (40 μL) 200 μL
BICD1-SOX5-20-GOAQ 20 (40 μL) 200 μL
BICD1-SOX5-20-GRRE 20 (40 μL) 200 μL
BICD1-SOX5-20-GROR 20 (40 μL) 200 μL
BICD1-SOX5-20-GRGO 20 (40 μL) 200 μL
BICD1-SOX5-20-GRGR 20 (40 μL) 200 μL
BICD1-SOX5-20-GRAQ 20 (40 μL) 200 μL
BICD1-SOX5-20-AQRE 20 (40 μL) 200 μL
BICD1-SOX5-20-AQOR 20 (40 μL) 200 μL
BICD1-SOX5-20-AQGO 20 (40 μL) 200 μL
BICD1-SOX5-20-AQGR 20 (40 μL) 200 μL
BICD1-SOX5-20-AQAQ 20 (40 μL) 200 μL

BICD1 Gene Summary

This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. [provided by RefSeq, Aug 2017]

Gene Name: BICD Cargo Adaptor 1

Chromosome: CHR12: 32260184 -32531141

Locus: 12p11.21

SOX5 Gene Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Gene Name: SRY-box 5

Chromosome: CHR12: 23685230 -24715380

Locus: 12p12.1

Gene Diseases

The BICD1 SOX5 Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.