BIN3-PEBP4 Fusion FISH Probe
The BIN3-PEBP4 Fusion FISH Probe is used to confirm a fusion of the BIN3 and PEBP4 genes. The fusion of the BIN3 and PEBP4 genes has been associated with Breast Invasive Carcinoma, and Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BIN3-PEBP4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-RERE | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-REOR | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-REGO | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-REGR | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-REAQ | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-ORRE | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-OROR | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-ORGO | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-ORAQ | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GORE | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GOOR | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GOGO | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GOGR | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GOAQ | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GRRE | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GROR | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GRGO | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GRGR | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-GRAQ | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-AQRE | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-AQOR | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-AQGO | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-AQGR | 20 (40 μL) | 200 μL |
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| BIN3-PEBP4-20-AQAQ | 20 (40 μL) | 200 μL |
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BIN3 Gene Summary
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008]
Gene Name: Bridging Integrator 3
Chromosome: CHR8: 22477946 -22526661
Locus: 8p21.3
PEBP4 Gene Summary
The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008]
Gene Name: Phosphatidylethanolamine Binding Protein 4
Chromosome: CHR8: 22570764 -22785421
Locus: 8p21.3
Gene Diseases
The BIN3 PEBP4 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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