BIRC6-ABCC11 Fusion FISH Probe
The BIRC6-ABCC11 Fusion FISH Probe is used to confirm a fusion of the BIRC6 and ABCC11 genes. The fusion of the BIRC6 and ABCC11 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BIRC6-ABCC11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-RERE | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-REOR | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-REGO | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-REGR | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-REAQ | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-ORRE | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-OROR | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-ORGO | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-ORAQ | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GORE | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GOOR | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GOGO | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GOGR | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GOAQ | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GRRE | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GROR | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GRGO | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GRGR | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-GRAQ | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-AQRE | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-AQOR | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-AQGO | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-AQGR | 20 (40 μL) | 200 μL |
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| BIRC6-ABCC11-20-AQAQ | 20 (40 μL) | 200 μL |
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BIRC6 Gene Summary
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. [provided by RefSeq, Jul 2008]
Gene Name: Baculoviral IAP Repeat Containing 6
Chromosome: CHR2: 32582095 -32843965
Locus: 2p22.3
ABCC11 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily C Member 11
Chromosome: CHR16: 48200821 -48269088
Locus: 16q12.1
Gene Diseases
The BIRC6 ABCC11 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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