BLNK-ZNF536 Fusion FISH Probe
The BLNK-ZNF536 Fusion FISH Probe is used to confirm a fusion of the BLNK and ZNF536 genes. The fusion of the BLNK and ZNF536 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BLNK-ZNF536-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-RERE | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-REOR | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-REGO | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-REGR | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-REAQ | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-ORRE | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-OROR | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-ORGO | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-ORAQ | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GORE | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GOOR | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GOGO | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GOGR | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GOAQ | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GRRE | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GROR | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GRGO | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GRGR | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-GRAQ | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-AQRE | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-AQOR | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-AQGO | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-AQGR | 20 (40 μL) | 200 μL |
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| BLNK-ZNF536-20-AQAQ | 20 (40 μL) | 200 μL |
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ZNF536 Gene Summary
The protein encoded by this gene is a highly conserved zinc finger protein. The encoded protein is most abundant in brain, where it negatively regulates neuronal differentiation. [provided by RefSeq, Sep 2015]
Gene Name: Zinc Finger Protein 536
Chromosome: CHR19: 30863327 -31048965
Locus: 19q12
BLNK Gene Summary
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
Gene Name: B-cell Linker
Chromosome: CHR10: 97951454 -98031333
Locus: 10q24.1
Gene Diseases
The BLNK ZNF536 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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