BRD4-CSN2 Fusion FISH Probe
The BRD4-CSN2 Fusion FISH Probe is used to confirm a fusion of the BRD4 and CSN2 genes. The fusion of the BRD4 and CSN2 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BRD4-CSN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-RERE | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-REOR | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-REGO | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-REGR | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-REAQ | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-ORRE | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-OROR | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-ORGO | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GORE | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GOOR | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GOGO | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GOGR | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GRRE | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GROR | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GRGO | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GRGR | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-AQRE | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-AQOR | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-AQGO | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-AQGR | 20 (40 μL) | 200 μL |
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| BRD4-CSN2-20-AQAQ | 20 (40 μL) | 200 μL |
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CSN2 Gene Summary
This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Name: Casein Beta
Chromosome: CHR4: 70820973 -70826726
Locus: 4q13.3
BRD4 Gene Summary
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Gene Name: Bromodomain Containing 4
Chromosome: CHR19: 15348300 -15391262
Locus: 19p13.12
Gene Diseases
The BRD4 CSN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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