BRF1-FOXN3 Fusion FISH Probe
The BRF1-FOXN3 Fusion FISH Probe is used to confirm a fusion of the BRF1 and FOXN3 genes. The fusion of the BRF1 and FOXN3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BRF1-FOXN3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-RERE | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-REOR | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-REGO | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-REGR | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-REAQ | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-ORRE | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-OROR | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-ORGO | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-ORAQ | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GORE | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GOOR | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GOGO | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GOGR | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GOAQ | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GRRE | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GROR | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GRGO | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GRGR | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-GRAQ | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-AQRE | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-AQOR | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-AQGO | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-AQGR | 20 (40 μL) | 200 μL |
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| BRF1-FOXN3-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXN3 Gene Summary
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box N3
Chromosome: CHR14: 89622515 -90085494
Locus: 14q31.3-q32.11
BRF1 Gene Summary
This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]
Gene Name: BRF1, RNA Polymerase III Transcription Initiation Factor Subunit
Chromosome: CHR14: 105675622 -105781914
Locus: 14q32.33
Gene Diseases
The BRF1 FOXN3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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