BRWD1-ABCA10 Fusion FISH Probe
The BRWD1-ABCA10 Fusion FISH Probe is used to confirm a fusion of the BRWD1 and ABCA10 genes. The fusion of the BRWD1 and ABCA10 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BRWD1-ABCA10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-RERE | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-REOR | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-REGO | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-REGR | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-REAQ | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-ORRE | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-OROR | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-ORGO | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-ORAQ | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GORE | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GOOR | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GOGO | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GOGR | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GOAQ | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GRRE | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GROR | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GRGO | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GRGR | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-GRAQ | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-AQRE | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-AQOR | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-AQGO | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-AQGR | 20 (40 μL) | 200 μL |
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| BRWD1-ABCA10-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCA10 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily A Member 10
Chromosome: CHR17: 67144147 -67240956
Locus: 17q24.3
BRWD1 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011]
Gene Name: Bromodomain And WD Repeat Domain Containing 1
Chromosome: CHR21: 40557403 -40685712
Locus: 21q22.2
Gene Diseases
The BRWD1 ABCA10 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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