SEARCH OUR PRODUCT CATALOG

BRWD1-LCA5L Fusion FISH Probe

The BRWD1-LCA5L Fusion FISH Probe is used to confirm a fusion of the BRWD1 and LCA5L genes. The fusion of the BRWD1 and LCA5L genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BRWD1-LCA5L-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
BRWD1-LCA5L-20-RERE 20 (40 μL) 200 μL
BRWD1-LCA5L-20-REOR 20 (40 μL) 200 μL
BRWD1-LCA5L-20-REGO 20 (40 μL) 200 μL
BRWD1-LCA5L-20-REGR 20 (40 μL) 200 μL
BRWD1-LCA5L-20-REAQ 20 (40 μL) 200 μL
BRWD1-LCA5L-20-ORRE 20 (40 μL) 200 μL
BRWD1-LCA5L-20-OROR 20 (40 μL) 200 μL
BRWD1-LCA5L-20-ORGO 20 (40 μL) 200 μL
BRWD1-LCA5L-20-ORAQ 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GORE 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GOOR 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GOGO 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GOGR 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GOAQ 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GRRE 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GROR 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GRGO 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GRGR 20 (40 μL) 200 μL
BRWD1-LCA5L-20-GRAQ 20 (40 μL) 200 μL
BRWD1-LCA5L-20-AQRE 20 (40 μL) 200 μL
BRWD1-LCA5L-20-AQOR 20 (40 μL) 200 μL
BRWD1-LCA5L-20-AQGO 20 (40 μL) 200 μL
BRWD1-LCA5L-20-AQGR 20 (40 μL) 200 μL
BRWD1-LCA5L-20-AQAQ 20 (40 μL) 200 μL

BRWD1 Gene Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011]

Gene Name: Bromodomain And WD Repeat Domain Containing 1

Chromosome: CHR21: 40557403 -40685712

Locus: 21q22.2

LCA5L Gene Summary

The LCA5L, Lebercilin Like (LCA5L) gene is located on chr21 :40777769-40816128 at 21q22.2.

Gene Name: LCA5L, Lebercilin Like

Chromosome: CHR21: 40777769 -40816128

Locus: 21q22.2

Gene Diseases

The BRWD1 LCA5L Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.