BTAF1-PTPRR Fusion FISH Probe
The BTAF1-PTPRR Fusion FISH Probe is used to confirm a fusion of the BTAF1 and PTPRR genes. The fusion of the BTAF1 and PTPRR genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BTAF1-PTPRR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-RERE | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-REOR | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-REGO | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-REGR | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-REAQ | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-ORRE | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-OROR | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-ORGO | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-ORAQ | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GORE | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GOOR | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GOGO | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GOGR | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GOAQ | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GRRE | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GROR | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GRGO | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GRGR | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-GRAQ | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-AQRE | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-AQOR | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-AQGO | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-AQGR | 20 (40 μL) | 200 μL |
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| BTAF1-PTPRR-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRR Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type R
Chromosome: CHR12: 71031852 -71314584
Locus: 12q15
BTAF1 Gene Summary
This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]
Gene Name: B-TFIID TATA-box Binding Protein Associated Factor 1
Chromosome: CHR10: 93683735 -93790080
Locus: 10q23.32
Gene Diseases
The BTAF1 PTPRR Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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