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BTBD2-AMZ2 Fusion FISH Probe

The BTBD2-AMZ2 Fusion FISH Probe is used to confirm a fusion of the BTBD2 and AMZ2 genes. The fusion of the BTBD2 and AMZ2 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BTBD2-AMZ2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
BTBD2-AMZ2-20-RERE 20 (40 μL) 200 μL
BTBD2-AMZ2-20-REOR 20 (40 μL) 200 μL
BTBD2-AMZ2-20-REGO 20 (40 μL) 200 μL
BTBD2-AMZ2-20-REGR 20 (40 μL) 200 μL
BTBD2-AMZ2-20-REAQ 20 (40 μL) 200 μL
BTBD2-AMZ2-20-ORRE 20 (40 μL) 200 μL
BTBD2-AMZ2-20-OROR 20 (40 μL) 200 μL
BTBD2-AMZ2-20-ORGO 20 (40 μL) 200 μL
BTBD2-AMZ2-20-ORAQ 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GORE 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GOOR 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GOGO 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GOGR 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GOAQ 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GRRE 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GROR 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GRGO 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GRGR 20 (40 μL) 200 μL
BTBD2-AMZ2-20-GRAQ 20 (40 μL) 200 μL
BTBD2-AMZ2-20-AQRE 20 (40 μL) 200 μL
BTBD2-AMZ2-20-AQOR 20 (40 μL) 200 μL
BTBD2-AMZ2-20-AQGO 20 (40 μL) 200 μL
BTBD2-AMZ2-20-AQGR 20 (40 μL) 200 μL
BTBD2-AMZ2-20-AQAQ 20 (40 μL) 200 μL

AMZ2 Gene Summary

The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]

Gene Name: Archaelysin Family Metallopeptidase 2

Chromosome: CHR17: 66244144 -66253305

Locus: 17q24.2

BTBD2 Gene Summary

The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. [provided by RefSeq, Jul 2008]

Gene Name: BTB Domain Containing 2

Chromosome: CHR19: 1985446 -2015702

Locus: 19p13.3

Gene Diseases

The BTBD2 AMZ2 Fusion has been associated with the following diseases:

Disease Name
Thymoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.