BTBD2-GTSE1 Fusion FISH Probe
The BTBD2-GTSE1 Fusion FISH Probe is used to confirm a fusion of the BTBD2 and GTSE1 genes. The fusion of the BTBD2 and GTSE1 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BTBD2-GTSE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-RERE | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-REOR | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-REGO | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-REGR | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-REAQ | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-ORRE | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-OROR | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-ORGO | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GORE | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GOOR | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GOGO | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GOGR | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GRRE | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GROR | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GRGO | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GRGR | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-AQRE | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-AQOR | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-AQGO | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-AQGR | 20 (40 μL) | 200 μL |
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| BTBD2-GTSE1-20-AQAQ | 20 (40 μL) | 200 μL |
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GTSE1 Gene Summary
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]
Gene Name: G2 And S-phase Expressed 1
Chromosome: CHR22: 46692637 -46726707
Locus: 22q13.31
BTBD2 Gene Summary
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. [provided by RefSeq, Jul 2008]
Gene Name: BTB Domain Containing 2
Chromosome: CHR19: 1985446 -2015702
Locus: 19p13.3
Gene Diseases
The BTBD2 GTSE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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