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BTN2A1-HIST1H2AC Fusion FISH Probe

The BTN2A1-HIST1H2AC Fusion FISH Probe is used to confirm a fusion of the BTN2A1 and HIST1H2AC genes. The fusion of the BTN2A1 and HIST1H2AC genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BTN2A1-HIST1H2AC-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-RERE 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-REOR 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-REGO 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-REGR 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-REAQ 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-ORRE 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-OROR 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-ORGO 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-ORAQ 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GORE 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GOOR 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GOGO 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GOGR 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GOAQ 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GRRE 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GROR 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GRGO 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GRGR 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-GRAQ 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-AQRE 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-AQOR 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-AQGO 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-AQGR 20 (40 μL) 200 μL
BTN2A1-HIST1H2AC-20-AQAQ 20 (40 μL) 200 μL

HIST1H2AC Gene Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

Gene Name: Histone Cluster 1 H2A Family Member C

Chromosome: CHR6: 26124372 -26124918

Locus: 6p22.2

BTN2A1 Gene Summary

This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

Gene Name: Butyrophilin Subfamily 2 Member A1

Chromosome: CHR6: 26458152 -26476849

Locus: 6p22.2

Gene Diseases

The BTN2A1 HIST1H2AC Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.