C10ORF118-GFRA1 Fusion FISH Probe
The C10ORF118-GFRA1 Fusion FISH Probe is used to confirm a fusion of the C10ORF118 and GFRA1 genes. The fusion of the C10ORF118 and GFRA1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C10ORF118-GFRA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-RERE | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-REOR | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-REGO | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-REGR | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-REAQ | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-ORRE | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-OROR | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-ORGO | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GORE | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GOOR | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GOGO | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GOGR | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GRRE | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GROR | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GRGO | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GRGR | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-AQRE | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-AQOR | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-AQGO | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-AQGR | 20 (40 μL) | 200 μL |
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| C10ORF118-GFRA1-20-AQAQ | 20 (40 μL) | 200 μL |
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GFRA1 Gene Summary
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: GDNF Family Receptor Alpha 1
Chromosome: CHR10: 117816441 -118033126
Locus: 10q25.3
Gene Diseases
The C10ORF118 GFRA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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