C12ORF66-NXF3 Fusion FISH Probe
The C12ORF66-NXF3 Fusion FISH Probe is used to confirm a fusion of the C12ORF66 and NXF3 genes. The fusion of the C12ORF66 and NXF3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C12ORF66-NXF3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-RERE | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-REOR | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-REGO | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-REGR | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-REAQ | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-ORRE | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-OROR | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-ORGO | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-ORAQ | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GORE | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GOOR | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GOGO | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GOGR | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GOAQ | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GRRE | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GROR | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GRGO | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GRGR | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-GRAQ | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-AQRE | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-AQOR | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-AQGO | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-AQGR | 20 (40 μL) | 200 μL |
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| C12ORF66-NXF3-20-AQAQ | 20 (40 μL) | 200 μL |
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NXF3 Gene Summary
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear RNA Export Factor 3
Chromosome: CHRX: 102330749 -102348022
Locus: Xq22.1
C12orf66 Gene Summary
The Chromosome 12 Open Reading Frame 66 (C12orf66) gene is located on chr12 :64586418-64616076 at 12q14.2.
Gene Name: Chromosome 12 Open Reading Frame 66
Chromosome: CHR12: 64586418 -64616076
Locus: 12q14.2
Gene Diseases
The C12ORF66 NXF3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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