C15ORF41-FBXL2 Fusion FISH Probe
The C15ORF41-FBXL2 Fusion FISH Probe is used to confirm a fusion of the C15ORF41 and FBXL2 genes. The fusion of the C15ORF41 and FBXL2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C15ORF41-FBXL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-RERE | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-REOR | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-REGO | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-REGR | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-REAQ | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-ORRE | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-OROR | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-ORGO | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GORE | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GOOR | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GOGO | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GOGR | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GRRE | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GROR | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GRGO | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GRGR | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-AQRE | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-AQOR | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-AQGO | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-AQGR | 20 (40 μL) | 200 μL |
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| C15ORF41-FBXL2-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXL2 Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Name: F-box And Leucine Rich Repeat Protein 2
Chromosome: CHR3: 33318933 -33428757
Locus: 3p22.3
C15orf41 Gene Summary
This gene encodes a protein with two predicted helix-turn-helix domains. Mutations in this gene were found in families with congenital dyserythropoietic anemia type Ib. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Gene Name: Chromosome 15 Open Reading Frame 41
Chromosome: CHR15: 36871811 -37102449
Locus: 15q14
Gene Diseases
The C15ORF41 FBXL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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