C15ORF41-RYR3 Fusion FISH Probe
The C15ORF41-RYR3 Fusion FISH Probe is used to confirm a fusion of the C15ORF41 and RYR3 genes. The fusion of the C15ORF41 and RYR3 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C15ORF41-RYR3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-RERE | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-REOR | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-REGO | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-REGR | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-REAQ | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-ORRE | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-OROR | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-ORGO | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-ORAQ | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GORE | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GOOR | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GOGO | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GOGR | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GOAQ | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GRRE | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GROR | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GRGO | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GRGR | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-GRAQ | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-AQRE | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-AQOR | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-AQGO | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-AQGR | 20 (40 μL) | 200 μL |
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| C15ORF41-RYR3-20-AQAQ | 20 (40 μL) | 200 μL |
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RYR3 Gene Summary
The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Ryanodine Receptor 3
Chromosome: CHR15: 33603176 -34158303
Locus: 15q13.3-q14
C15orf41 Gene Summary
This gene encodes a protein with two predicted helix-turn-helix domains. Mutations in this gene were found in families with congenital dyserythropoietic anemia type Ib. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Gene Name: Chromosome 15 Open Reading Frame 41
Chromosome: CHR15: 36871811 -37102449
Locus: 15q14
Gene Diseases
The C15ORF41 RYR3 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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