C18ORF10-DSG1 Fusion FISH Probe
The C18ORF10-DSG1 Fusion FISH Probe is used to confirm a fusion of the C18ORF10 and DSG1 genes. The fusion of the C18ORF10 and DSG1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C18ORF10-DSG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-RERE | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-REOR | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-REGO | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-REGR | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-REAQ | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-ORRE | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-OROR | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-ORGO | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GORE | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GOOR | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GOGO | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GOGR | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GRRE | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GROR | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GRGO | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GRGR | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-AQRE | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-AQOR | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-AQGO | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-AQGR | 20 (40 μL) | 200 μL |
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| C18ORF10-DSG1-20-AQAQ | 20 (40 μL) | 200 μL |
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DSG1 Gene Summary
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]
Gene Name: Desmoglein 1
Chromosome: CHR18: 28898051 -28937393
Locus: 18q12.1
Gene Diseases
The C18ORF10 DSG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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