C18ORF45-PACS1 Fusion FISH Probe
The C18ORF45-PACS1 Fusion FISH Probe is used to confirm a fusion of the C18ORF45 and PACS1 genes. The fusion of the C18ORF45 and PACS1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C18ORF45-PACS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-RERE | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-REOR | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-REGO | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-REGR | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-REAQ | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-ORRE | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-OROR | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-ORGO | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GORE | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GOOR | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GOGO | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GOGR | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GRRE | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GROR | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GRGO | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GRGR | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-AQRE | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-AQOR | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-AQGO | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-AQGR | 20 (40 μL) | 200 μL |
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| C18ORF45-PACS1-20-AQAQ | 20 (40 μL) | 200 μL |
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PACS1 Gene Summary
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]
Gene Name: Phosphofurin Acidic Cluster Sorting Protein 1
Chromosome: CHR11: 65837823 -66012213
Locus: 11q13.1-q13.2
Gene Diseases
The C18ORF45 PACS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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