CABYR-OSBPL1A Fusion FISH Probe
The CABYR-OSBPL1A Fusion FISH Probe is used to confirm a fusion of the CABYR and OSBPL1A genes. The fusion of the CABYR and OSBPL1A genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CABYR-OSBPL1A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-RERE | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-REOR | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-REGO | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-REGR | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-REAQ | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-ORRE | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-OROR | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-ORGO | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-ORAQ | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GORE | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GOOR | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GOGO | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GOGR | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GOAQ | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GRRE | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GROR | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GRGO | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GRGR | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-GRAQ | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-AQRE | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-AQOR | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-AQGO | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-AQGR | 20 (40 μL) | 200 μL |
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| CABYR-OSBPL1A-20-AQAQ | 20 (40 μL) | 200 μL |
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CABYR Gene Summary
To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
Gene Name: Calcium Binding Tyrosine Phosphorylation Regulated
Chromosome: CHR18: 21718954 -21741564
Locus: 18q11.2
OSBPL1A Gene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Oxysterol Binding Protein Like 1A
Chromosome: CHR18: 21742010 -21977833
Locus: 18q11.2
Gene Diseases
The CABYR OSBPL1A Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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