CACNA2D3-FOXP1 Fusion FISH Probe
The CACNA2D3-FOXP1 Fusion FISH Probe is used to confirm a fusion of the CACNA2D3 and FOXP1 genes. The fusion of the CACNA2D3 and FOXP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CACNA2D3-FOXP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-RERE | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-REOR | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-REGO | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-REGR | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-REAQ | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-ORRE | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-OROR | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-ORGO | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GORE | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GOOR | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GOGO | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GOGR | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GRRE | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GROR | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GRGO | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GRGR | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-AQRE | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-AQOR | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-AQGO | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-AQGR | 20 (40 μL) | 200 μL |
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| CACNA2D3-FOXP1-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXP1 Gene Summary
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box P1
Chromosome: CHR3: 71004735 -71633140
Locus: 3p13
CACNA2D3 Gene Summary
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Alpha2delta 3
Chromosome: CHR3: 54156692 -55108584
Locus: 3p21.1-p14.3
Gene Diseases
The CACNA2D3 FOXP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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