CAMTA2-LCK Fusion FISH Probe
The CAMTA2-LCK Fusion FISH Probe is used to confirm a fusion of the CAMTA2 and LCK genes. The fusion of the CAMTA2 and LCK genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CAMTA2-LCK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-RERE | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-REOR | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-REGO | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-REGR | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-REAQ | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-ORRE | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-OROR | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-ORGO | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-ORAQ | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GORE | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GOOR | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GOGO | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GOGR | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GOAQ | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GRRE | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GROR | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GRGO | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GRGR | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-GRAQ | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-AQRE | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-AQOR | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-AQGO | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-AQGR | 20 (40 μL) | 200 μL |
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| CAMTA2-LCK-20-AQAQ | 20 (40 μL) | 200 μL |
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LCK Gene Summary
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]
Gene Name: LCK Proto-oncogene, Src Family Tyrosine Kinase
Chromosome: CHR1: 32716839 -32751766
Locus: 1p35.2
CAMTA2 Gene Summary
The protein encoded by this gene is a member of the calmodulin-binding transcription activator protein family. Members of this family share a common domain structure that consists of a transcription activation domain, a DNA-binding domain, and a calmodulin-binding domain. The encoded protein may be a transcriptional coactivator of genes involved in cardiac growth. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010]
Gene Name: Calmodulin Binding Transcription Activator 2
Chromosome: CHR17: 4871286 -4890960
Locus: 17p13.2
Gene Diseases
The CAMTA2 LCK Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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