CAP1-MACF1 Fusion FISH Probe
The CAP1-MACF1 Fusion FISH Probe is used to confirm a fusion of the CAP1 and MACF1 genes. The fusion of the CAP1 and MACF1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CAP1-MACF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-RERE | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-REOR | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-REGO | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-REGR | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-REAQ | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-ORRE | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-OROR | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-ORGO | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GORE | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GOOR | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GOGO | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GOGR | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GRRE | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GROR | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GRGO | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GRGR | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-AQRE | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-AQOR | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-AQGO | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-AQGR | 20 (40 μL) | 200 μL |
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| CAP1-MACF1-20-AQAQ | 20 (40 μL) | 200 μL |
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CAP1 Gene Summary
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2016]
Gene Name: Cyclase Associated Actin Cytoskeleton Regulatory Protein 1
Chromosome: CHR1: 40506254 -40538321
Locus: 1p34.2
MACF1 Gene Summary
This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]
Gene Name: Microtubule-actin Crosslinking Factor 1
Chromosome: CHR1: 39547088 -39952810
Locus: 1p34.3
Gene Diseases
The CAP1 MACF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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