CAPNS1-CCDC149 Fusion FISH Probe
The CAPNS1-CCDC149 Fusion FISH Probe is used to confirm a fusion of the CAPNS1 and CCDC149 genes. The fusion of the CAPNS1 and CCDC149 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CAPNS1-CCDC149-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-RERE | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-REOR | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-REGO | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-REGR | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-REAQ | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-ORRE | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-OROR | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-ORGO | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-ORAQ | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GORE | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GOOR | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GOGO | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GOGR | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GOAQ | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GRRE | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GROR | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GRGO | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GRGR | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-GRAQ | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-AQRE | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-AQOR | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-AQGO | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-AQGR | 20 (40 μL) | 200 μL |
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| CAPNS1-CCDC149-20-AQAQ | 20 (40 μL) | 200 μL |
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CAPNS1 Gene Summary
This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Gene Name: Calpain Small Subunit 1
Chromosome: CHR19: 36630917 -36641255
Locus: 19q13.12
CCDC149 Gene Summary
The Coiled-coil Domain Containing 149 (CCDC149) gene is located on chr4 :24807738-24981826 at 4p15.2.
Gene Name: Coiled-coil Domain Containing 149
Chromosome: CHR4: 24807738 -24981826
Locus: 4p15.2
Gene Diseases
The CAPNS1 CCDC149 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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