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CARM1-KLF11 Fusion FISH Probe

The CARM1-KLF11 Fusion FISH Probe is used to confirm a fusion of the CARM1 and KLF11 genes. The fusion of the CARM1 and KLF11 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CARM1-KLF11-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CARM1-KLF11-20-RERE 20 (40 μL) 200 μL
CARM1-KLF11-20-REOR 20 (40 μL) 200 μL
CARM1-KLF11-20-REGO 20 (40 μL) 200 μL
CARM1-KLF11-20-REGR 20 (40 μL) 200 μL
CARM1-KLF11-20-REAQ 20 (40 μL) 200 μL
CARM1-KLF11-20-ORRE 20 (40 μL) 200 μL
CARM1-KLF11-20-OROR 20 (40 μL) 200 μL
CARM1-KLF11-20-ORGO 20 (40 μL) 200 μL
CARM1-KLF11-20-ORAQ 20 (40 μL) 200 μL
CARM1-KLF11-20-GORE 20 (40 μL) 200 μL
CARM1-KLF11-20-GOOR 20 (40 μL) 200 μL
CARM1-KLF11-20-GOGO 20 (40 μL) 200 μL
CARM1-KLF11-20-GOGR 20 (40 μL) 200 μL
CARM1-KLF11-20-GOAQ 20 (40 μL) 200 μL
CARM1-KLF11-20-GRRE 20 (40 μL) 200 μL
CARM1-KLF11-20-GROR 20 (40 μL) 200 μL
CARM1-KLF11-20-GRGO 20 (40 μL) 200 μL
CARM1-KLF11-20-GRGR 20 (40 μL) 200 μL
CARM1-KLF11-20-GRAQ 20 (40 μL) 200 μL
CARM1-KLF11-20-AQRE 20 (40 μL) 200 μL
CARM1-KLF11-20-AQOR 20 (40 μL) 200 μL
CARM1-KLF11-20-AQGO 20 (40 μL) 200 μL
CARM1-KLF11-20-AQGR 20 (40 μL) 200 μL
CARM1-KLF11-20-AQAQ 20 (40 μL) 200 μL

KLF11 Gene Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

Gene Name: Kruppel Like Factor 11

Chromosome: CHR2: 10183681 -10194963

Locus: 2p25.1

CARM1 Gene Summary

This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. [provided by RefSeq, Aug 2013]

Gene Name: Coactivator Associated Arginine Methyltransferase 1

Chromosome: CHR19: 10982252 -11033448

Locus: 19p13.2

Gene Diseases

The CARM1 KLF11 Fusion has been associated with the following diseases:

Disease Name
Colon Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.