CASC3-ZNF254 Fusion FISH Probe
The CASC3-ZNF254 Fusion FISH Probe is used to confirm a fusion of the CASC3 and ZNF254 genes. The fusion of the CASC3 and ZNF254 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CASC3-ZNF254-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-RERE | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-REOR | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-REGO | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-REGR | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-REAQ | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-ORRE | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-OROR | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-ORGO | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-ORAQ | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GORE | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GOOR | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GOGO | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GOGR | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GOAQ | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GRRE | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GROR | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GRGO | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GRGR | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-GRAQ | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-AQRE | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-AQOR | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-AQGO | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-AQGR | 20 (40 μL) | 200 μL |
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| CASC3-ZNF254-20-AQAQ | 20 (40 μL) | 200 μL |
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ZNF254 Gene Summary
Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM, Jul 2002]
Gene Name: Zinc Finger Protein 254
Chromosome: CHR19: 24269975 -24312654
Locus: 19p12
CASC3 Gene Summary
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]
Gene Name: Cancer Susceptibility 3
Chromosome: CHR17: 38296506 -38328431
Locus: 17q21.1
Gene Diseases
The CASC3 ZNF254 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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