CCNC-MICAL1 Fusion FISH Probe
The CCNC-MICAL1 Fusion FISH Probe is used to confirm a fusion of the CCNC and MICAL1 genes. The fusion of the CCNC and MICAL1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCNC-MICAL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-RERE | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-REOR | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-REGO | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-REGR | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-REAQ | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-ORRE | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-OROR | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-ORGO | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GORE | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GOOR | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GOGO | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GOGR | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GRRE | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GROR | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GRGO | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GRGR | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-AQRE | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-AQOR | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-AQGO | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-AQGR | 20 (40 μL) | 200 μL |
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| CCNC-MICAL1-20-AQAQ | 20 (40 μL) | 200 μL |
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CCNC Gene Summary
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Cyclin C
Chromosome: CHR6: 99990262 -100016690
Locus: 6q16.2
MICAL1 Gene Summary
This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Name: Microtubule Associated Monooxygenase, Calponin And LIM Domain Containing 1
Chromosome: CHR6: 109765265 -109777190
Locus: 6q21
Gene Diseases
The CCNC MICAL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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