CCNY-DENND1A Fusion FISH Probe
The CCNY-DENND1A Fusion FISH Probe is used to confirm a fusion of the CCNY and DENND1A genes. The fusion of the CCNY and DENND1A genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCNY-DENND1A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-RERE | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-REOR | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-REGO | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-REGR | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-REAQ | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-ORRE | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-OROR | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-ORGO | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GORE | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GOOR | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GOGO | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GOGR | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GRRE | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GROR | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GRGO | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GRGR | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-AQRE | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-AQOR | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-AQGO | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-AQGR | 20 (40 μL) | 200 μL |
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| CCNY-DENND1A-20-AQAQ | 20 (40 μL) | 200 μL |
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DENND1A Gene Summary
Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]
Gene Name: DENN Domain Containing 1A
Chromosome: CHR9: 126141932 -126692417
Locus: 9q33.3
CCNY Gene Summary
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009]
Gene Name: Cyclin Y
Chromosome: CHR10: 35535952 -35860847
Locus: 10p11.21
Gene Diseases
The CCNY DENND1A Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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