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CCT2-KRT78 Fusion FISH Probe

The CCT2-KRT78 Fusion FISH Probe is used to confirm a fusion of the CCT2 and KRT78 genes. The fusion of the CCT2 and KRT78 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CCT2-KRT78-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CCT2-KRT78-20-RERE 20 (40 μL) 200 μL
CCT2-KRT78-20-REOR 20 (40 μL) 200 μL
CCT2-KRT78-20-REGO 20 (40 μL) 200 μL
CCT2-KRT78-20-REGR 20 (40 μL) 200 μL
CCT2-KRT78-20-REAQ 20 (40 μL) 200 μL
CCT2-KRT78-20-ORRE 20 (40 μL) 200 μL
CCT2-KRT78-20-OROR 20 (40 μL) 200 μL
CCT2-KRT78-20-ORGO 20 (40 μL) 200 μL
CCT2-KRT78-20-ORAQ 20 (40 μL) 200 μL
CCT2-KRT78-20-GORE 20 (40 μL) 200 μL
CCT2-KRT78-20-GOOR 20 (40 μL) 200 μL
CCT2-KRT78-20-GOGO 20 (40 μL) 200 μL
CCT2-KRT78-20-GOGR 20 (40 μL) 200 μL
CCT2-KRT78-20-GOAQ 20 (40 μL) 200 μL
CCT2-KRT78-20-GRRE 20 (40 μL) 200 μL
CCT2-KRT78-20-GROR 20 (40 μL) 200 μL
CCT2-KRT78-20-GRGO 20 (40 μL) 200 μL
CCT2-KRT78-20-GRGR 20 (40 μL) 200 μL
CCT2-KRT78-20-GRAQ 20 (40 μL) 200 μL
CCT2-KRT78-20-AQRE 20 (40 μL) 200 μL
CCT2-KRT78-20-AQOR 20 (40 μL) 200 μL
CCT2-KRT78-20-AQGO 20 (40 μL) 200 μL
CCT2-KRT78-20-AQGR 20 (40 μL) 200 μL
CCT2-KRT78-20-AQAQ 20 (40 μL) 200 μL

CCT2 Gene Summary

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Gene Name: Chaperonin Containing TCP1 Subunit 2

Chromosome: CHR12: 69979207 -69995357

Locus: 12q15

KRT78 Gene Summary

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified. [provided by RefSeq, Jul 2008]

Gene Name: Keratin 78

Chromosome: CHR12: 53232745 -53242778

Locus: 12q13.13

Gene Diseases

The CCT2 KRT78 Fusion has been associated with the following diseases:

Disease Name
Adrenocortical Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.