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CCT3-SQSTM1 Fusion FISH Probe

The CCT3-SQSTM1 Fusion FISH Probe is used to confirm a fusion of the CCT3 and SQSTM1 genes. The fusion of the CCT3 and SQSTM1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CCT3-SQSTM1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CCT3-SQSTM1-20-RERE 20 (40 μL) 200 μL
CCT3-SQSTM1-20-REOR 20 (40 μL) 200 μL
CCT3-SQSTM1-20-REGO 20 (40 μL) 200 μL
CCT3-SQSTM1-20-REGR 20 (40 μL) 200 μL
CCT3-SQSTM1-20-REAQ 20 (40 μL) 200 μL
CCT3-SQSTM1-20-ORRE 20 (40 μL) 200 μL
CCT3-SQSTM1-20-OROR 20 (40 μL) 200 μL
CCT3-SQSTM1-20-ORGO 20 (40 μL) 200 μL
CCT3-SQSTM1-20-ORAQ 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GORE 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GOOR 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GOGO 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GOGR 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GOAQ 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GRRE 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GROR 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GRGO 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GRGR 20 (40 μL) 200 μL
CCT3-SQSTM1-20-GRAQ 20 (40 μL) 200 μL
CCT3-SQSTM1-20-AQRE 20 (40 μL) 200 μL
CCT3-SQSTM1-20-AQOR 20 (40 μL) 200 μL
CCT3-SQSTM1-20-AQGO 20 (40 μL) 200 μL
CCT3-SQSTM1-20-AQGR 20 (40 μL) 200 μL
CCT3-SQSTM1-20-AQAQ 20 (40 μL) 200 μL

CCT3 Gene Summary

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010]

Gene Name: Chaperonin Containing TCP1 Subunit 3

Chromosome: CHR1: 156278751 -156308206

Locus: 1q22

SQSTM1 Gene Summary

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]

Gene Name: Sequestosome 1

Chromosome: CHR5: 179233387 -179265077

Locus: 5q35.3

Gene Diseases

The CCT3 SQSTM1 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.