CD74-ROS1 Fusion FISH Probe
The CD74-ROS1 Fusion FISH Probe is used to confirm a fusion of the CD74 and ROS1 genes. The fusion of the CD74 and ROS1 genes has been associated with Lung Adenocarcinoma, and Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD74-ROS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CD74-ROS1-20-AQAQ | 20 (40 μL) | 200 μL |
|
CD74 Gene Summary
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Name: CD74 Molecule
Chromosome: CHR5: 149781199 -149792499
Locus: 5q33.1
ROS1 Gene Summary
This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]
Gene Name: ROS Proto-oncogene 1, Receptor Tyrosine Kinase
Chromosome: CHR6: 117609529 -117747018
Locus: 6q22.1
Gene Diseases
The CD74 ROS1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|