CD81-SURF4 Fusion FISH Probe
The CD81-SURF4 Fusion FISH Probe is used to confirm a fusion of the CD81 and SURF4 genes. The fusion of the CD81 and SURF4 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD81-SURF4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-RERE | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-REOR | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-REGO | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-REGR | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-REAQ | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-ORRE | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-OROR | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-ORGO | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GORE | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GOOR | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GOGO | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GOGR | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GRRE | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GROR | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GRGO | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GRGR | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-AQRE | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-AQOR | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-AQGO | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-AQGR | 20 (40 μL) | 200 μL |
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| CD81-SURF4-20-AQAQ | 20 (40 μL) | 200 μL |
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CD81 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Name: CD81 Molecule
Chromosome: CHR11: 2398546 -2418649
Locus: 11p15.5
SURF4 Gene Summary
This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat protein I to the cytosol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Surfeit 4
Chromosome: CHR9: 136228339 -136242970
Locus: 9q34.2
Gene Diseases
The CD81 SURF4 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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