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CDC27-CCT6B Fusion FISH Probe

The CDC27-CCT6B Fusion FISH Probe is used to confirm a fusion of the CDC27 and CCT6B genes. The fusion of the CDC27 and CCT6B genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CDC27-CCT6B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CDC27-CCT6B-20-RERE 20 (40 μL) 200 μL
CDC27-CCT6B-20-REOR 20 (40 μL) 200 μL
CDC27-CCT6B-20-REGO 20 (40 μL) 200 μL
CDC27-CCT6B-20-REGR 20 (40 μL) 200 μL
CDC27-CCT6B-20-REAQ 20 (40 μL) 200 μL
CDC27-CCT6B-20-ORRE 20 (40 μL) 200 μL
CDC27-CCT6B-20-OROR 20 (40 μL) 200 μL
CDC27-CCT6B-20-ORGO 20 (40 μL) 200 μL
CDC27-CCT6B-20-ORAQ 20 (40 μL) 200 μL
CDC27-CCT6B-20-GORE 20 (40 μL) 200 μL
CDC27-CCT6B-20-GOOR 20 (40 μL) 200 μL
CDC27-CCT6B-20-GOGO 20 (40 μL) 200 μL
CDC27-CCT6B-20-GOGR 20 (40 μL) 200 μL
CDC27-CCT6B-20-GOAQ 20 (40 μL) 200 μL
CDC27-CCT6B-20-GRRE 20 (40 μL) 200 μL
CDC27-CCT6B-20-GROR 20 (40 μL) 200 μL
CDC27-CCT6B-20-GRGO 20 (40 μL) 200 μL
CDC27-CCT6B-20-GRGR 20 (40 μL) 200 μL
CDC27-CCT6B-20-GRAQ 20 (40 μL) 200 μL
CDC27-CCT6B-20-AQRE 20 (40 μL) 200 μL
CDC27-CCT6B-20-AQOR 20 (40 μL) 200 μL
CDC27-CCT6B-20-AQGO 20 (40 μL) 200 μL
CDC27-CCT6B-20-AQGR 20 (40 μL) 200 μL
CDC27-CCT6B-20-AQAQ 20 (40 μL) 200 μL

CDC27 Gene Summary

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate, which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats, which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 22 and Y. [provided by RefSeq, May 2014]

Gene Name: Cell Division Cycle 27

Chromosome: CHR17: 45195310 -45266665

Locus: 17q21.32

CCT6B Gene Summary

This gene encodes a molecular chaperone that is a member of the chaperonin-containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Gene Name: Chaperonin Containing TCP1 Subunit 6B

Chromosome: CHR17: 33254877 -33288528

Locus: 17q12

Gene Diseases

The CDC27 CCT6B Fusion has been associated with the following diseases:

Disease Name
Esophageal Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.