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CDC42BPB-ZFYVE1 Fusion FISH Probe

The CDC42BPB-ZFYVE1 Fusion FISH Probe is used to confirm a fusion of the CDC42BPB and ZFYVE1 genes. The fusion of the CDC42BPB and ZFYVE1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CDC42BPB-ZFYVE1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-RERE 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-REOR 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-REGO 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-REGR 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-REAQ 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-ORRE 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-OROR 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-ORGO 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-ORAQ 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GORE 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GOOR 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GOGO 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GOGR 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GOAQ 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GRRE 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GROR 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GRGO 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GRGR 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-GRAQ 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-AQRE 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-AQOR 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-AQGO 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-AQGR 20 (40 μL) 200 μL
CDC42BPB-ZFYVE1-20-AQAQ 20 (40 μL) 200 μL

CDC42BPB Gene Summary

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]

Gene Name: CDC42 Binding Protein Kinase Beta

Chromosome: CHR14: 103398715 -103523742

Locus: 14q32.32

ZFYVE1 Gene Summary

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Gene Name: Zinc Finger FYVE-type Containing 1

Chromosome: CHR14: 73436158 -73493920

Locus: 14q24.2

Gene Diseases

The CDC42BPB ZFYVE1 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.