CDH3-CHKA Fusion FISH Probe
The CDH3-CHKA Fusion FISH Probe is used to confirm a fusion of the CDH3 and CHKA genes. The fusion of the CDH3 and CHKA genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDH3-CHKA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-RERE | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-REOR | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-REGO | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-REGR | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-REAQ | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-ORRE | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-OROR | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-ORGO | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GORE | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GOOR | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GOGO | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GOGR | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GRRE | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GROR | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GRGO | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GRGR | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-AQRE | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-AQOR | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-AQGO | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-AQGR | 20 (40 μL) | 200 μL |
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| CDH3-CHKA-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH3 Gene Summary
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]
Gene Name: Cadherin 3
Chromosome: CHR16: 68678150 -68732957
Locus: 16q22.1
CHKA Gene Summary
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Choline Kinase Alpha
Chromosome: CHR11: 67820325 -67888858
Locus: 11q13.2
Gene Diseases
The CDH3 CHKA Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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