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CDK14-TFEC Fusion FISH Probe

The CDK14-TFEC Fusion FISH Probe is used to confirm a fusion of the CDK14 and TFEC genes. The fusion of the CDK14 and TFEC genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CDK14-TFEC-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CDK14-TFEC-20-RERE 20 (40 μL) 200 μL
CDK14-TFEC-20-REOR 20 (40 μL) 200 μL
CDK14-TFEC-20-REGO 20 (40 μL) 200 μL
CDK14-TFEC-20-REGR 20 (40 μL) 200 μL
CDK14-TFEC-20-REAQ 20 (40 μL) 200 μL
CDK14-TFEC-20-ORRE 20 (40 μL) 200 μL
CDK14-TFEC-20-OROR 20 (40 μL) 200 μL
CDK14-TFEC-20-ORGO 20 (40 μL) 200 μL
CDK14-TFEC-20-ORAQ 20 (40 μL) 200 μL
CDK14-TFEC-20-GORE 20 (40 μL) 200 μL
CDK14-TFEC-20-GOOR 20 (40 μL) 200 μL
CDK14-TFEC-20-GOGO 20 (40 μL) 200 μL
CDK14-TFEC-20-GOGR 20 (40 μL) 200 μL
CDK14-TFEC-20-GOAQ 20 (40 μL) 200 μL
CDK14-TFEC-20-GRRE 20 (40 μL) 200 μL
CDK14-TFEC-20-GROR 20 (40 μL) 200 μL
CDK14-TFEC-20-GRGO 20 (40 μL) 200 μL
CDK14-TFEC-20-GRGR 20 (40 μL) 200 μL
CDK14-TFEC-20-GRAQ 20 (40 μL) 200 μL
CDK14-TFEC-20-AQRE 20 (40 μL) 200 μL
CDK14-TFEC-20-AQOR 20 (40 μL) 200 μL
CDK14-TFEC-20-AQGO 20 (40 μL) 200 μL
CDK14-TFEC-20-AQGR 20 (40 μL) 200 μL
CDK14-TFEC-20-AQAQ 20 (40 μL) 200 μL

CDK14 Gene Summary

PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]

Gene Name: Cyclin Dependent Kinase 14

Chromosome: CHR7: 90338711 -90839904

Locus: 7q21.13

TFEC Gene Summary

This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Gene Name: Transcription Factor EC

Chromosome: CHR7: 115575201 -115670798

Locus: 7q31.2

Gene Diseases

The CDK14 TFEC Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.